Laureates of the Japan Prize
-
Dr. C. David Allis
- Nationality:
USA
- Date of Birth:
22 March 1951
Outline of Achievements
The 2014 Japan Prize
Major Awards
| 2002 |
Dickson Prize in Biomedical Sciences |
| 2003 |
Massry Prize |
| 2007 |
Gairdner Foundation International Award |
| 2008 |
ASBMB-Merck Award |
| 2011 |
Lewis S. Rosenstiel Award |
Academic Degrees
| 1973 |
University of Cincinnati, B.S. in Biology |
| 1975 |
Indiana University, M.S. in Biology |
| 1978 |
Indiana University, Ph.D. in Biology |
Professional Career
| 1978-1981 |
Post Doctoral Fellow, the University of Rochester |
| 1981-1990 |
Assistant, Associate and Professor, Dept. of Biochemistry and Cell Biology,Baylor College of Medicine |
| 1990-1995 |
Professor, Dept. of Biology, Syracuse University |
| 1995-1998 |
Marie and Joseph Wilson Professor of Biology and Professor of Oncology, University of Rochester |
| 1998-2003 |
Harry F. Byrd, Jr. Professor of Biochemistry and Molecular Genetics, Professor of Microbiology and Member of the Center for Cell Signaling, University of Virginia Health System |
| 2003-Present |
Joy and Jack Fishman Professor and Head of the Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University |
Major Publications
- Brownell, J.E., and Allis, C.D. Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84, 843-851, doi:S0092-8674(00)81063-6 [pii] (1996).
- Sassone-Corsi, P., Mizzen, C.M., Cheung, P., Crosio, C., Monaco, M., Jacquot, S., Hanauer, A., and Allis, C.D. Requirement of Rsk-2 for epidermal growth factor- activated phosphorylation of histone H3. Science 285, 886-891, doi:7736 [pii] (1999).
- Strahl, B. D. and Allis, C. D. The language of covalent histone modifications. Nature 403, 41-45, doi:10.1038/47412 (2000).
- Jenuwein, T. and Allis, C.D. Translating the histone code. Science 293, 1074-1080 (2001).
- Wysocka, J., Swigut, T., Xiao, H., Landry, J., Kauer, M., Tackett, A., Chait, B., Brivanlou, A.H., Wu, C. and Allis, C.D. A PHD finger in the largest subunit of NURF couples histone H3 K4 trimethylation with chromatin remodeling. Nature 442, 86-90, PMID: 16728978 (2006).
- Wang, G.G., Song, J., Wang, Z., Dormann, H., Casadio, F., Li, H., Patel, D. and Allis, C.D. Haematopietic malignancies initiated by dysregulation of an H3K4me3-engaging PHD finger. Nature 459, 847-851, PMID: 19430464 (2009).
- Goldberg A.D., Banaszynski L.A., Noh K.M., Lewis P.W., Elsässer S.J., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver, R.C., Miller J.C., Lee Y.L., Boydston E.A., Holmes M.C., Gregory P.D., Greally J.M., Rafii S., Yang C., Scambler P.J., Garrick D., Gibbons R.J., Higgs D.R., Cristea I.M., Urnov F.D., Zheng D., Allis C.D. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 140, 678-691, PMID: 20211137 (2010).
- Lewis, P.W., Mueller, M.M., Koletsky, M.S., Cordero, F., Lin, S., Banaszynski, L.A., Garcia, B.A., Muir, T.W., Becher, O.J. and Allis C.D. Inhibition of PRC2 activity by gain-of-function mutations in pediatric glioblastoma mutation. Science 17, 857-861, PMID: 23539183 (2013).
