Laureates of the Japan Prize

Chief, Biochemistry Division, National Cancer Center Research Institute, Tokyo

1. Nakahara, W., Fukuoka, F. and Sugimura, T. Carcinogenic action of 4-nitroquinoline 1-oxide. Gann, 48:129-137, 1957.
2. Sugimura, T., Nagao, M. and Okada, K. Carcinogenic action of N-methyl-N'-nitro-N-nitrosoguanidine. Nature, 210: 962-963, 1966.
3. Sugimura, T., Okabe, K. and Nagao, M. The metabolism of 4-nitroquinoline 1-oxide, a carcinogen. III: An enzyme catalyzing the conversion of 4-nitroquinoline 1-oxide to 4-hydroxyaminoquinoline 1-oxide in rat liver and hepatomas. Cancer Res., 26: 1717-1721, 1966.
4. Matsushima, T., Kobuna, I. and Sugimura, T. In vivo interaction of 4-nitroquinoline 1-oxide and its derivatives with DNA. Nature, 216: 508, 1967.
5. Sugimura, T., and Fujimura, S. Tumor production in glandular stomach of rat by N-methyl-N'-nitro-N-nitrosoguanidine. Nature, 216:943-944, 1967.
6. Sugimura, T., Otake, H. and Matsushima, T. Single strand scissions of DNA caused by a carcinogen, 4-hydroxyaminoquinoline 1-oxide. Nature, 218:392, 1968.
7. Sugimura, T., Nagao, M., Kawachi, T., Honda, M., Yahagi, T., Seino, Y., Sato, S., Matsukura, N., Matsushima, T., Shirai, A., Sawamura, M. and Matsumoto, H. Mutagen-carcinogens in food, with special reference to highly mutagenic pyrolytic products in broiled foods. In : H.H. Hiatt, J.D. Watson, and J.A. Winsten (eds), Origins of Human Cancer, pp. 1561-1577, Cold Spring Harbor, NY:Cold Spring Harbor Laboratory, 1977.
8. Sugimura, T. Studies on environmental chemical carcinogenesis in Japan. Science, 233: 312-318, 1986.
9. Sugimura, T. Multiple carcinogenesis: A 1992 perspective. Science, 258:603-607, 1992.
10. Sugimura, T., Nagao, M. and Wakabayashi, K. Heterocyclic amines in cooked foods: Candidates for causation of common cancers. J. Natl. Cancer Inst., 86:2-4, 1994.
11. Kakiuchi, H., Watanabe, M., Ushijima, T., Toyota, M., Imai, K., Weisburger, J.H., Sugimura, T. and Nagao, M. Specific 5'-GGGA-3' -5'-GAA-3' mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine. Proc. Natl. Acad. Sci. USA, 92: 910-914, 1995.
12. Toyota, M., Ushijima, T., Weisburger, J.H., Hosoya, Y., Canzian, F., Rivenson, A., Imai, K., Sugimura, T. and Nagao, M. Microsatellite instability and loss of heterozygosity on chromosome 10 in rat mammary tumors induced by 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine. Molecular Carcinogenesis, 15: 176-182, 1996.

• Prize of Princess Takamatsu Cancer Research Fund (Experimental Studies on Stomach Cancer) (1969)
• Prize of Takeda Medical Foundation (Studies on Gastric Cancer and Cancr Biochemistry) (1974)
• Prize of Fujihara Foundation (Studies on poly (ADP-Ribose)) (1975)
• Japan Academy Prize and Imperial Prize (Studies on Experimental Stomach Cancer) (1976)
• Fogarty Scholar in Residence, National Institutes of Health, USA (1977)
• The Outstanding Work Award of the Environmental Mutagen Society of the United States (The Relation between Mutagens and Carcinogens and the Identification of Environmental Mutagens) (1978)
• The Order of Cultural Merits of the Japanese Government 1981 The Ernst W. Bertner Memorial Award (1978)
• The Charles S. Mott Prize of General Motors Cancer Research Foundation (1981)
• The Tomizo Yoshida Prize, Japanese Cancer Association (1992)
• The 1st Award of the Environmental Mutagen Society of Japan (1994)

• Honorary Member of the American Association for Cancer Research (1980)
• Foreign Associate of the National Academy of Sciences, USA (1982)
• Member of the Japan Academy (1982)
• Honorary Member of the Pharmaceutical Society of Japan (1986)
• Honorary Member of the Environmental Mutagen Society of Japan (1987)
• Foreign Member of the Royal Netherlands Academy of Arts and Sciences (Division for Sciences) (1987)
• Foreign Member of the Royal Swedish Academy of Sciences (Class for Medical Sciences) (1987)
• Honorary Member of the American Society for Biochemistry and Molecular Biology (1988)
• Honorary Member of Japanese Biochemical Society (1990)
• Honorary Member of the Korean Cancer Association (1992)
• Honorary Degree of Doctor of Science of the Thomas Jefferson University (1994)
• Foreign Associate of the Institute of Medicine, National Academy of Sciences, USA (1994)
• Honorary Member of Japanese Cancer Association (1994)

• Japan Society of Clinical Biochemistry and Metabolism
• Japan Pancreas Society
• Japan Society of Cancer Epidemiology
• Japan Society for Cancer Therapy
• Japan Society of Gene Therapy
• Japanese Association for Animal Cell Technology
• Japanese Biochemical Society
• Japanese Cancer Association
• Japanese Environmental Mutagen Society
• Japanese Society of Nutrition and Food Science
• Molecular Biology Society of Japan