Laureates of the Japan Prize

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Dr. Kimishige Ishizaka

2000 (16th) Japan Prize Laureate

Field
Host Defense
Achievement
Discovery of Immunoglobulin E and mechanisms of IgE-mediated allergic reactions
Commemorative Lecture
Identification of Ige and the Mechanisms of Allergy
Nationality: Japan
Date of Birth: December 3 1925
Academic Degrees:
1948 M.D. Ph.D .(The University of Tokyo)
Professional Career:
1953-1962 Chief,Department of Serology, Division of Immunoserology, National Institute of Health, Japan
1957-1959 Research Fellow, Division of Chemistry and Chemical Engineering, California Institute of Technology
1962-1965 Assistant Professor of Microbiology, University of Colorado Medical School
1962-1970 Chief, Department of Immunology, Children's Asthma Research Institute and Hospital
1965-1970 Associate Professor of Microbiology, University of Colorado Medical School
1970-1981 O'Neill Professor of Medicine and Microbiology, The Johns Hopkins University School of Medicine
1970-1989 Professor of Biology, The Johns Hopkins University Faculty of Arts and Science
1974-1980 Professor, Kyoto University Research Laboratory for Immunology
1981-1988 Director, Subdepartment of Immunology, The Johns Hopkins University School of Medicine
1981-1989 O'Neill Professor of Immunology and Medicine, The Johns Hopkins University School of Medicine
1989-1996 Scientific Director, La Jolla Institute for Allergy and Immunology
1989-1996 Adjunct Professor, Department of Medicine, University of California, San Diego
1990-1996 President, La Jolla Institute for Allergy and Immunology
1996 to Present President Emeritus, La Jolla Institute for Allergy and Immunology
Title: President Emeritus, La Jolla Institute for Allergy and Immunology
Major Publications and Scientific Papers:
  1. Ishizaka, K. Ishizaka, T. and Hornbrook, M. M. Physicochemical properties of human reaginic antibody. IV. Presence of a unique immunoglobulin as a carrier of reaginic activity. J. Immunol. 97:75 1966
  2. Ishizaka, K. Ishizaka, T. and Hornbrook, M. M. Physicochemical properties of reaginic antibody. V. Correlation of reaginic activity with γE globulin antibody. J. Immunol. 97:840 1996
  3. Ishizaka, K. and Ishizaka, T. Identification of γE-antibodies as a carrier of reaginic activity. J. Immunol. 99:1187 1967
  4. Ishizaka, K., Tomioka, H. and Ishizaka, T. Mechanism of passive sensitization. I.Presence of IgE and IgG molecules on human leukocytes. J. Immunol. 105:1459 1970
  5. Ishizaka, K. and Ishizaka, T. Immune mechanism of reversed- type reaginic hypersensitivity. J. Immunol. 103:588 1969
  6. Ishizaka, T. and Ishizaka, K. Triggering of histamine release from rat mast cells by divalent antibodies against IgE receptors. J. Immunol., 120: 800 1978
Major Awards and Honors Received:
  • Passano Foundation Award (1972)
  • Paul Ehrich and Ludwig Darmstaedter Preis (1973)
  • Gairdner Foundation International Award (1973)
  • Takeda Medical Award (1973)
  • The First Scientific Achievement Award of International Association of Allergology (1974)
  • Asahi Cultural Award (1974)
  • Emperor's Award, The Japan Academy Award (1974)
  • The Order of Cultural Merit (1974)
  • Modern Medicine Award for Distinguished Achievement (1977)
  • Borden Award of Association of American Medical Colleges (1979)
  • Pioneer of Modern Allergy Award from American College of Allergy (1982)
  • American College of Physicians Award for Achievement in Medical Science (1985)
  • The First Order of Merit, The Order of the Sacred Treasure (1999)
Membership in Academic Institutions and Societies:
  • The American Academy of Allergy
  • American Association of Immunologists
  • Collegium Internationale Allergologicum
  • National Academy of Sciences, USA
  • American Academy of Arts and Sciences, USA
  • Emeritus Member Japanese Society of Allergology
  • Emeritus Member of Japanese Society for Immunology
  • The Japan Academy

( At the time of receipt of the Prize )

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