Laureates of the Japan Prize

photo

Dr. Erkki Ruoslahti

2005 (21st) Japan Prize Laureate

Field
Cell Biology
Achievement
Fundamental contribution in elucidating the molecular mechanisms of cell adhesion
Commemorative Lecture
From integrin-binding RGD peptides to vascular homing peptides
Nationality: USA
Date of Birth: February 16 1940
Academic Degrees:
1961 B.M. in Medicine, University of Helsinki, Finland
1965 M.D. in Medicine, University of Helsinki
1967 Ph.D. in Immunology, University of Helsinki
Professional Career:
1970-75 Assistant Professor and Acting Associate Professor Department of Serology and Bacteriology, University of Helsinki, Finland
1975-76 Professor, Bacteriology and Serology, University of Turku, Finland
1976 Senior Research Scientist, Dept. Immunology, City of Hope, National Medical Center, USA
1976-79 Director, Immunology, Div. Immunology, City of Hope
1979-80 Associate Scientific Director, The Burnham Institute
1980-95 Scientific Director, The Burnham Institute
1982-89 Vice President and Chief Operating Officer, The Burnham Institute
1989-2001 President and CEO, The Burnham Institute Director, NCI Cancer Center, The Burnham Institute
1980-2004 Adjunct Professor, Pathology Department, University of California, San Diego
2002-present Distinguished Professor, The Burnham Institute
2003-present Adjunct Professor, Department of Bioengineering, University of California, San Diego
Title: Distinguished Professor, The Burnham Institute
Major Publications:
  1. Pierschbacher, M.D .and Ruoslahti, E. (1984) Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature 309, 30-33.
  2. Pytela, R., Pierschbacher, M.D. and Ruoslahti, E. (1985) Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor. Cell 40, 191-198.
  3. Suzuki, S., Argraves, W.S., Pytela, R., Arai, H., Krusius, T., Pierschbacher, M.D. and Ruoslahti, E. (1986) cDNA and amino acid sequences of the cell adhesion protein receptor recognizing vitronectin reveal a transmembrane domain and homologies with other adhesion protein receptors. Proc. Natl. Acad. Sci. USA 83, 8614-8618.
  4. Argraves, W.S., Suzuki, S., Arai, H., Thompson, K., Pierschbacher, M.D. and Ruoslahti, E. (1987) Amino acid sequence of the human fibronectin receptor. J. Cell Biol. 105, 1183-190.
  5. Suzuki, S., Argraves, W.S., Arai, H., Languino, L.R., Pierschbacher, M.D. and Ruoslahti, E. (1987) Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs. J. Biol. Chem. 262, 14080-14085.
  6. Ruoslahti, E. and Pierschbacher, M.D. (1987) New perspectives in cell adhesion: RGD and integrins. Science 238, 491-497.
Major Awards Received:
  • Outstanding Investigator Award National Cancer Institute (1986-93)
  • G.H.A. Clowes Award American (1990)
  • Robert J. and Claire Pasarow Foundation Award (1991)
  • Honorary Doctor of Medicine, University of Lund (1991)
  • Leila Gruber Cancer Research Award (1993)
  • Abbott Award (International Society for Oncodevelopmentl Biology and Medicine) (1995)
  • Gairdner Foundation International Award (1997)
  • Jacobaeus International Prize (1998)
  • The Jubilee Award, The British Biomedical Society (2003)
Major Honors:
  • Member, Societas Scientiarum Fennica (Finnish Academy of Sciences) (1989)
  • Fellow, American Academy of Arts and Sciences (1993)
  • Knight, Order of the White Rose of Finland (1994)
  • Nobel Fellow, Karolinska Institute, Stockholm (1995)
  • Member, U.S. National Academy of Sciences (1999)
  • Member, European Molecular Biology Organization (2001)
  • Member, Institute of Medicine of the U.S. National Academies (2002)

( At the time of receipt of the Prize )

More about the Laureates

30 Years of Japan Prize

page top