Japan Prize Laureates

Laureates of the Japan Prize

Dr. Bruce N. Ames

Dr. Bruce N. Ames

  • Nationality:
  • Date of Birth:
    16 December 1928

Outline of Achievements

Outline of Achievements

The 1997 Japan Prize

Major Awards

1964 Eli Lilly Award of the American Chemical Society
1966 Arthur Flemming Award (as Outstanding Young Government Employee)
1976 Lewis Rosenstiel Award
1976 FASEB/3M Award for Research in Life Sciences
1976 E.R.D.A. Distinguished Associate Award
1977 Environmental Mutagen Society Award
1977 Cal. Tech. Distinguished Alumni Award
1978 Simon Shubitz Cancer Prize
1978 Felix Wankel Research Award
1979 John Scott Medal
1980 Bolton L. Corson Medal
1980 New Brunswick Lectureship Award of A.S.M.
1981 Wadsworth Award
1983 Charles S. Mott Prize, General Motors Cancer Research Foundation
1983 Gairdner Foundation Award (Canada)
1985 Tyler Prize for Environmental Achievement
1986 Spencer Award (American Chemical Society)
1991 Gold Medal , American Institute of Chemists
1992 Glenn Foundation Award, Gerontological Society of America
1995 Lovelace Award for Excellence in Environmental Health Research
1996 Honda Prize, Honda Foundation (Japan)

Major Honors

1970 American Academy of Arts and Sciences
1972 National Academy of Sciences
1980 Fellow of the American Association for the Advancement of Science
1987 Honorary Member of Japanese Cancer Association
1989 Foreign Member of the Royal Swedish Academy of Sciences

Membership in Academic Institutions and Societies

American Chemical Society
American Society of Biological Chemists
Genetics Society of America
American Society for Microbiology
Environmental Mutagen Society
American Association for Cancer Research
Society of Toxicology
Federation of American Scientists

Academic Degrees

1950 Cornell University, B.A.
1953 California Institute of Technology, Ph. D.
Biochemistry Major with Prof. H. K. Mitchell;
Chemistry and Genetics Minors

Professional Career

1953-54 Postdoctoral Fellow (U.S.P.H.S.) at National Institutes of Health with Dr. B. L. Horecker
1954-60 Biochemist at the National Institutes of Health
1961 Sabbatical year as N.S.F. Senior Fellow in laboratories of F.H. C.Crick in Cambridge, England, and F. Jacob in Paris, France
1962-67 Chief, Section of Microbial Genetics, Laboratory of Molecular Biology, N.I.A.M.D., National Institutes of Health
1968-Present Professor, Division of Biochemistry and Molecular Biology, University of California, Berkeley
1983-89 Chairman, Division of Biochemistry and Molecualr Biology, University of California, Berkeley
1979-Present Director, National Institute of Environmental Health Sciences Center, University of California, Berkeley


  • Professor of Biochemistry and Molecular Biology, University of California, Berkeley

Major Publications and Scientific Papers

  • Martin, R.G. and Ames, B.N. A method for determining the sedimentation behavior of enzymes: Application to protein mixtures. J.Biol. Chem. 236:1372-1379, 1961.
  • Ames, B.N. and Whitefield, Jr., H.J. Frameshift mutagenesis in Salmonella. Cold Spring Harbor Symposia on Quantitative Biology, 31:221-225, 1966.
  • McCann, J., Spingarn, N.E., Kobori, J. and Ames, B.N. Detection of carcinogens as mutagens: Bacterial tester strains with R factor plasmids. Proc. Natl. Acad. Sci. USA, 72:979-988, 1975.
  • McCann, J., Choi, E., Yamasaki, E. and Ames, B.N. Detection of carcinogens as mutagens in the Salmonella/microsome test: Assay of 300 chemicals. Proc. Natl. Acad. Sci. USA, 72: 5135-5139,1975.
  • Maron, D.M. and Ames, B.N. Revised methods for the Salmonella mutagenicity test. Mutation Res., 113:173-215, 1983.
  • Ames, B.N. and Gold, L.S. Chemical Carcinogenesis: Too Many Rodent Carcinogens. Proc. Natl. Acad. Sci. USA, 87:7772-7776, 1990.
  • Ames, B.N., Profet, M. and Gold, L.S. Dietary Pesticides (99.99% All Natural). Proc. Natl. Acad. Sci. USA, 87:7777-7781, 1990.
  • Ames, B.N., Profet, M. and Gold, L.S. Nature's Chemicals and Synthetic Chemicals: Comparative Toxicology. Proc. Natl. Acad. Sci. USA, 87:7782-7786, 1990.
  • Ames, B.N., Shigenaga, M.K. and Hagen, T.M. Oxidants, Antioxidants, and the Degenerative Diseases of Aging. Proc. Natl. Acad. Sci. USA, 90:7915-7922, 1993.
  • Shigenaga, M.K., Hagen, T.M. and Ames, B.N. Oxidative Damage and Mitochondrial Decay in Aging. Proc. Natl. Acad. Sci. USA, 91:10771-10778, 1994.
  • Gee, P., Maron, D.M. and Ames, B.N. Detection and classification of mutagens: A set of base-specific Salmonella tester strains. Proc. Natl. Acad. Sci. USA, 91:11606-11610, 1994.
  • Ames, B.N., Cold, L.S. and Willett, W.C. The causes and prevention of cancer. Proc. Natl. Acad. Sci. USA, 92: 5258-5265, 1995.
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