Japan Prize Laureates

Laureates of the Japan Prize

Dr. Anne McLaren

Dr. Anne McLaren

  • Nationality:
  • Date of Birth:

Outline of Achievements

Outline of Achievements

The 2002 Japan Prize

Major Awards and Honors Received

1967 Scientific Medal, Zoological Society, London
1975 Fellow of the Royal Society
1986 Fellow of the Royal College of Obstetricians and Gynaecologists
1988 Foreign Member of Polish Academy of Sciences
1990 Royal Medal, The Royal Society
1993 Dame Commander of the Order of the British Empire (DBE)
1995 Corresponding Member of Slovenian Academy of Sciences and Arts
1998 Founder Fellow, Academy of Medical Sciences
1999 Foreign Member of the Russian Academy of Sciences

Membership in Academic Institutions and Societies

The Royal Society
Royal Institution 3. British Society for Developmental Biology
Genetical Society
Society for the Study of Fertility
Zoological Society of London
British Society for Population Studies
ational Mouse Club
uropean Molecular Biology Organisation
European Society for Human Reproduction and Embryology
International Society of Differentiation

Academic Degrees

1949 M.A. University of Oxford
1952 Ph.D. University of Oxford

Professional Career

1952-55 Research Fellow, University College London
1955-59 Research Fellow, Royal Veterinary College of London
1959-74 Member staff, Agricultural Research Council (ARC)
Unit of Animal Genetics, University of Edinburgh
1974-92 Director, Medical Research Council (MRC) Mammalian Development Unit
1991-96 Foreign Secretary, Royal Society
1991 Fullerian Professor of Physiology, Royal Institution
1992-Present Present Principal Research Associate
Wellcome Trust/Cancer Research Campaign (CRC) Institute
1993-94 President, British Association for the Advancement of Science


  • Principal Research Associate, Wellcome Trust / CRC Institute

Major Publications and Scientific Papers

  • McLaren, A. and Biggers, J.D. (1958) Successful development and birth of mice cultivated in vitro as early embryos. Nature 182, 877-878.
  • McLaren, A. and Michie, D. (1958) Factors affecting vertebral variation in mice.4. Experimental proof of the uterine basis of a maternal effect.JEEM 6, 645-659.
  • McLaren, A. and Michie, D. (1959) Superpregnancy in the mouse. Implantation and foetal immortality after induced superovulation in females of various ages. J exp Biol 36, 281-300.
  • Healy, M. J.R., McLaren, A. and Michie, D. (1960) Foetal growth in the mouse. Proc Roy Soc B 153, 367-379. Wellcome Trust/Cancer Research Campaign (CRC) Institute.
  • McLaren, A. (1964) Immunological control of fertility in female mice. Nature 201, 582-585.
  • McLaren, A. (1965) Genetic and environmental effects on foetal and placental growth in mice. J Reprod Fert 2, 79-98.
  • McLaren, A. (1969) Stimulus and response during early pregnancy in the mouse. Nature 221, 739-741.
  • McLaren, A. and Bowman, P. (1969) Mouse chimaeras derived from fusion of embryos differing by nine genetic factors. Nature 224, 238-240.
  • McLaren, A. (1972) Numerology of development. Nature 239, 274-276.
  • McLaren, A. (1975) Sex chimaerism and germ cell distribution in a series of chimaeric mice. J Embryol exp Morph 33, 205-216.
  • De Felici, M. and Mclaren, A. (1982) Isolation of mouse primordial gem cells. Exp Cell Res 142, 477-482.
  • McLaren, A., Simpson, E., Tomonari, K., Chandler, P. and Hogg, H. (1984) Male sexual differentiation in mice lacking H-Y antigen. Nature 312, 552-555.
  • McLaren, A. (1988) The developmental history of female germ cells in mammals. In: Oxford Reviews of Reproductive Biology Chapter 4 Vol. 10, 162-179.
  • McLaren, A., Simpson, E.,Epplen, J. T., Studer, R., Koopman, P., Evans, E. P., and Burgoyne, P. S., (1988) Location of the genes controlling H-Y antigen expression and testis determination on the mouse Y chromosome. Proc Natl Acad Sci 85, 6442-6445.
  • McLaren, A. and Buehr, M. (1990) Development of mouse germ cells in cultures of fetal gonads. Cell Differentiation and Development 31, 185-195.
  • Ginsburg, M., Snow, M. H. L. and McLaren, A. (1990) Primordial germ cells in the mouse embryo gastrulation. Development 110, 521-528.
  • McLaren, A. (1995) Primordial germ cells in mammals In: Organization of the early vertebrate embryo (eds N Zagris, A M Duprat, A J Duston), Plenum Press, New York, pp.1-9.
  • McLaren, A. and Southee, D. (1997) Entry of mouse germ cells into meiosis. Dev Biol 187, 107-113.
  • Durcova-Hills, G., Ainscough, J.E. and McLaren, A. (2001) Pluripotential stem cells derived from migrating primordial cells. Differentiation 68, 220-226.
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