Japan Prize Laureates

Laureates of the Japan Prize

Dr. Seiji Ogawa

Dr. Seiji Ogawa

  • Nationality:
  • Date of Birth:
    19 January 1934

Outline of Achievements

Outline of Achievements

The 2003 Japan Prize

  • Field:
    Visualizing Techniques in Medicine
  • Achievement:
    Discovery of the principle for functional magnetic resonance imaging
  • Lecture:
    A Way to Learn Brain Function

Major Awards and Honors Received

1967 Eastman Kodak Award in Chemistry for PhD student
1995 Gold Medal Award from Society of Magnetic Resonance in Medicine
1996 Biological Physics Prize from The American Physical Society
1998 Nakayama Prize from Nakayama Foundation for Human Science, Japan
1999 Asahi Prize from The Asahi Shimbun Cultural Foundation, Japan

Membership in Academic Institutions and Societies

Member of International Society of Magnetic Resonance in Medicine
Member of Society for Neuroscience

Academic Degrees

1957 B.S. The University of Tokyo
1967 Ph.D. Stanford University

Professional Career

1962-64 Research Associate, Radiation Research Laboratories
Mellon Institute, Pittsburgh
1968-80 Member of the Technical Staff, Biophysics Research
Bell Laboratories, AT & T
1984-96 Distinguished Member of the Technical Staff
Principal Investigator
Biophysics Research
1996-2001 Distinguished Member of the Technical Staff
Principal Investigator
Biological Computation Research
Bell Laboratories, Lucent Technologies
2001 March Visiting Professor, Biophysics/Physiology Department
Albert Einstein College of Medicine, Yeshiva University, Bronx, New York
2001- Present Director, Ogawa Laboratories for Brain Function Research
Hamano Life Science Research Foundation


  • Director, Ogawa Laboratories for Brain Function Research, Hamano Life Science Research Foundation

Major Books and Papers

  • S. Ogawa, H. M. McConnell and R. Horowitz, "Overlapping Conformation Changes in Spin-Label Hemoglobin", Proc. Natl. Acad. Sci. (USA), 61: 401-405 (1968)
  • R. G. Shulman, S. Ogawa, K. Wurthrich, T. Yamane, J. Peisach and W. E. Blumberg, "Absence of "Heme-Heme" Interaction in Hemoglobin", Science, 165: 251-257 (1969)
  • S. Ogawa and R. G. Shulman, "High Resolution Nuclear Magnetic Resonance Spectra of Hemoglobin:III The Half Ligated State and Allosteric Interaction", J. Mol. Biol., 70: 314-335 (1972)
  • S. Ogawa, T. M. Lee, A. S. Nayak and P. Glynn, "Oxygenation Sensitive Contrast in Magnetic Resonance Image of Rodent Brain at High Magnetic Fields", Magn. Reson. Med., 14: 68-78 (1990).
  • S. Ogawa, T. M. Lee, A. R. Kay and D. W. Tank, "Brain Magnetic Resonance Imaging with Contrast Dependent on Blood Oxygenation", Proc. Natl. Acad. Sci. (USA), 87: 9868-9872 (1990).
  • S. Ogawa, D. W. Tank, R. Menon, J. M. Ellermann, S.-G. Kim, H. Merkle and K. Ugurbil, "Intrinsic Signal Changes Accompanying Sensory Stimulation: Functional BrainMapping With Magnetic Resonance Imaging", Proc. Natl. Acad. Sci. (USA), 89: 5951-5955 (1992).
  • W. Denk, R. M. Keolian, S. Ogawa and L. W. Jelinski, "Oscillatory Flow in the Cochlea Visualized by Novel Magnetic Resonance Imaging Technique", Proc. Natl. Acad. Sci. (USA), 90: 1595-1598 (1993).
  • S. Ogawa, R. S. Menon, D. W. Tank, S-G. Kim, H. Merkle, J. M. Ellermann and K. Ugurbil, "Functional Brain Mapping by Blood Oxygenation Level-Dependent Contrast Magnetic Resonance Imaging: A Comparison of Signal Characteristics with a Biophysical Model", Biophysical Journal, 64: March (1993)
  • P. P. Mitra, S. Ogawa, X. Hu and K. Ugurbil, "The Nature of Spatiotemporal Changes in Cerebral Hemodynamics as Manifested in Functional Magnetic Resonance Imaging",Magnetic Resonance in Medicine, 37: 511-518 (1997)
  • Seiji Ogawa, Tso-Ming Lee, Ray Stepnoski, Wei Chen, Xiao-Hong Zhu, and Kamil Ugurbil, "An approach to probe some neural systems interaction by functional MRI at neural time scale down to milliseconds", Proc. Natl. Acad. Sci. (USA), 97: 11026-11031 (2000)
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