Japan Prize Laureates

Laureates of the Japan Prize

Dr. C. David Allis

Dr. C. David Allis

  • Nationality:
  • Date of Birth:
    22 March 1951

Outline of Achievements

Outline of Achievements

The 2014 Japan Prize

Major Awards

2002 Dickson Prize in Biomedical Sciences
2003 Massry Prize
2007 Gairdner Foundation International Award
2008 ASBMB-Merck Award
2011 Lewis S. Rosenstiel Award

Academic Degrees

1973 University of Cincinnati, B.S. in Biology
1975 Indiana University, M.S. in Biology
1978 Indiana University, Ph.D. in Biology

Professional Career

1978-1981 Post Doctoral Fellow, the University of Rochester
1981-1990 Assistant, Associate and Professor, Dept. of Biochemistry and Cell Biology,Baylor College of Medicine
1990-1995 Professor, Dept. of Biology, Syracuse University
1995-1998 Marie and Joseph Wilson Professor of Biology and Professor of Oncology, University of Rochester
1998-2003 Harry F. Byrd, Jr. Professor of Biochemistry and Molecular Genetics, Professor of Microbiology and Member of the Center for Cell Signaling, University of Virginia Health System
2003-Present Joy and Jack Fishman Professor and Head of the Laboratory of Chromatin Biology and Epigenetics, The Rockefeller University

Major Publications

  • Brownell, J.E., and Allis, C.D. Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84, 843-851, doi:S0092-8674(00)81063-6 [pii] (1996).
  • Sassone-Corsi, P., Mizzen, C.M., Cheung, P., Crosio, C., Monaco, M., Jacquot, S., Hanauer, A., and Allis, C.D. Requirement of Rsk-2 for epidermal growth factor- activated phosphorylation of histone H3. Science 285, 886-891, doi:7736 [pii] (1999).
  • Strahl, B. D. and Allis, C. D. The language of covalent histone modifications. Nature 403, 41-45, doi:10.1038/47412 (2000).
  • Jenuwein, T. and Allis, C.D. Translating the histone code. Science 293, 1074-1080 (2001).
  • Wysocka, J., Swigut, T., Xiao, H., Landry, J., Kauer, M., Tackett, A., Chait, B., Brivanlou, A.H., Wu, C. and Allis, C.D. A PHD finger in the largest subunit of NURF couples histone H3 K4 trimethylation with chromatin remodeling. Nature 442, 86-90, PMID: 16728978 (2006).
  • Wang, G.G., Song, J., Wang, Z., Dormann, H., Casadio, F., Li, H., Patel, D. and Allis, C.D. Haematopietic malignancies initiated by dysregulation of an H3K4me3-engaging PHD finger. Nature 459, 847-851, PMID: 19430464 (2009).
  • Goldberg A.D., Banaszynski L.A., Noh K.M., Lewis P.W., Elsässer S.J., Stadler S., Dewell S., Law M., Guo X., Li X., Wen D., Chapgier A., DeKelver, R.C., Miller J.C., Lee Y.L., Boydston E.A., Holmes M.C., Gregory P.D., Greally J.M., Rafii S., Yang C., Scambler P.J., Garrick D., Gibbons R.J., Higgs D.R., Cristea I.M., Urnov F.D., Zheng D., Allis C.D. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 140, 678-691, PMID: 20211137 (2010).
  • Lewis, P.W., Mueller, M.M., Koletsky, M.S., Cordero, F., Lin, S., Banaszynski, L.A., Garcia, B.A., Muir, T.W., Becher, O.J. and Allis C.D. Inhibition of PRC2 activity by gain-of-function mutations in pediatric glioblastoma mutation. Science 17, 857-861, PMID: 23539183 (2013).
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