Laureates of the Japan Prize


Theodore Friedmann, M.D., MA (Oxon)

2015 Japan Prize Laureate

Medical Science and Medicinal Science
Proposal of the concept of gene therapy and its clinical applications
Commemorative Lecture
Gene therapy - A 45 year journey from concept to a new medicine
Nationality: United States of America
Date of Birth: June 16, 1935
Academic Degrees:
1956 A.B. in Chemistry from University of Pennsylvania
1960 M.D. from University of Pennsylvania
1995 M.A. from University of Oxford
Professional Career:
1960-1962 Children's Hospital Medical Center, Boston, Massachusetts
1962-1963 U.S. Air Force, Captain, 10th Tac., Hospital, Alconbury, England
1963-1964 University of Cambridge, England, Research Fellow in Colloid Science
1964-1965 Children's Hospital Medical Center, Boston, Massachusetts, and Teaching and Research Fellow, Harvard University
1965-1968 National Institutes of Health, Bethesda, Maryland
1969-1973 University of California, San Diego, Assistant Professor of Pediatrics
1973-1981 University of California, San Diego, Associate Professor of Pediatrics
1981-Present University of California, San Diego, Professor of Pediatrics
University of California, San Diego
Department of Pediatrics
9500 Gilman Drive, La Jolla, CA 92093-0634, U.S.A.
Major Publications:
  1. Friedmann T, Roblin R. Gene therapy for human genetic disease? Science 175(25): 949-955, 1972.
  2. Willis RC, Jolly DJ, Miller AD, Plent MM, Esty AC, Anderson PJ, Chang HC, Jones OW, Seegmiller JE, Friedmann T. Partial phenotypic correction of human Lesch-Nyhan (hypoxanthine-guanine phosphoribosyltransferase-deficient) lymphoblasts with a transmissible retroviral vector. J Biol Chem 259(12): 7842-7849, 1984.
  3. Miller AD, Eckner RJ, Jolly DJ, Friedmann T, Verma IM. Expression of a retrovirus encoding human HPRT in mice. Science 225(4662): 630-632, 1984.
  4. Yee JK, Moores JC, Jolly DJ, Wolff JA, Respess JG, Friedmann T. Gene expression from transcriptionally disabled retroviral vectors. Proc Natl Acad Sci U S A 84(15): 5197-5201, 4987.
  5. Emi, N., Friedmann, T. and Yee, J.-K., “Pseudotype Formation of Murine Leukemia Virus with the G Protein of Vesicular Stomatitis Virus,” J. Virol. 65, 1202-1207 (1991)
Major Awards:
  • 1984-85 UCSD's Faculty Research Lecturer Award
  • 1992 University of California, Chancellor’s Associates Award for Excellence in Research
  • 1995 The 1995 H.C. Jacobæus Prize of the Nordic Research Committee and Nordic Insulin Foundation, Lund, Sweden
  • 1996 The 1996 Cross of Honor for Science and the Arts, Republic of Austria
  • 1996 Salvador Zubiran Medal of Mexico
  • 1996 The Newton-Abraham Visiting Professorship at the University of Oxford
  • 2003 The Award of Merit from National Institutes of Health (NIH)
  • 2006 Distinguished Graduate Award from the University of Pennsylvania
  • 2006 President of American Society of Gene Therapy

(As of January 2015)

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