Japan Prize Laureates

Laureates of the Japan Prize

Prof. Bert Vogelstein

Bert Vogelstein, M.D.

  • Nationality:
  • Date of Birth:
    2 June 1949 (71)

Outline of Achievements

Outline of Achievements

The 2021 Japan Prize

  • Field:
    Medical Science, Medicinal Science
  • Achievement:
    For their pioneering work in conceptualizing a multi-step model of carcinogenesis and its application and impact on improving cancer diagnosis and therapy
  • Lecture:
    Cancer Genes & Their Implications for Patients

Award and Honor

1990 Bristol Myers Squibb Award
1992 Canada Gairdner International Award
American Cancer Society Medal of Honor
1993 Shacknai Memorial Prize
Baxter Award
Pezcoller Foundation Award
Richard Lounsbery Award
1994 Ernst Schering Prize
Dickson Prize,
Howard Taylor Ricketts Award
Passano Award
1995 Karnofsky Memorial Award,
Clowes Memorial Award
1997 William Beaumont Prize
Golden Plate Award
1998 Louisa Gross Horwitz Prize
William Allan Award
Paul Ehrlich and Ludwig Darmstaedter Prize
2000 Charles S. Mott Prize
2001 Harvey Prize
2003 John Scott Award
2004 Prince of Asturias Awards
2007 Pasarow Award
2011 Charles Rodolphe Brupbacher Prize
2013 Breakthrough Prize
2014 Warren Triennial Prize
2015 Paul Janssen Award
2018 Dan David Prize
2019 Albany Medical Center Prize
Gruber Prize in Genetics
2020 Jessie Stevenson Kovalenko Medal


1974 M.D. Johns Hopkins University School of Medicine

Professional History

1976-1978 Research associate, National Cancer Institute
1978 Assistant professor, Johns Hopkins University
1989 Professor, Johns Hopkins University
1995 Investigator, Howard Hughes Medical Institute
2012 Co-director, Ludwig Center for at Johns Hopkins
2019 Director, Lustgarten Dedicated Laboratory for Pancreatic Cancer Research

Key Publications

  • Vogelstein, B., Fearon, E.R., Hamilton, S.R., Kern, S.E., Preisinger, A.C., Leppert, M., Nakamura, Y., White, R., Smits, A.M.M., Bos, J.L. Genetic alterations during colorectal tumor development. New England Journal of Medicine 319: 525-532, 1988.
  • Baker, S.J., Fearon, E.R., Nigro, J.M., Hamilton, S.R., Preisinger, A.C., Jessup, J.M., vanTuinen, P., Ledbetter, D.H., Barker, D.F., Nakamura, Y., White, R., Vogelstein, B. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 244: 217-221, 1989.
  • Nishisho, I., Nakamura, Y., Miyoshi, Y., Miki, Y., Ando, H., Horii, A., Koyama, K., Utsunomiya, J., Baba, S., Hedge, P., Markham, A., Krush, A.J., Petersen, G., Hamilton, S.R., Nilbert, M.C., Levy, D.B., Bryan, T.M., Preisinger, A.C., Smith, K.J., Su, L.-K., Kinzler, K.W., Vogelstein, B. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 253: 665-669, 1991.
  • Kern, S.E., Kinzler, K.W., Bruskin, A., Jarosz, D., Friedman, P., Prives, C., Vogelstein, B. Identification of p53 as a sequence-specific DNA-binding protein. Science 252: 1708-1711, 1991.
  • Sidransky, D., Tokino, T., Hamilton, S.R., Kinzler, K.W., Levin, B., Frost, P., and Vogelstein, B. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 256: 102-105, 1992.
  • Wood, L.D., Parsons, D.W., Jones, S., Lin, J., Sjöblom, T., Leary, R,J., Shen, D., Boca, S.M., Barber, T., Ptak, J., Silliman, N., Szabo, S., Dezso, Z., Ustyanksky, V., Nikolskaya, T., Nikolsky, Y., Karchin, R., Wilson, P.A., Kaminker, J.A., Zhang, Z., Croshaw, R., Willis, J., Dawson, D., Shipitsin, M., Willson, J.K.V., Sukumar, S., Polyak, K., Park, B.H., Pethiyagoda, C.L., Pant, P.V.K., Ballinger, D.G., Sparks, A.B., Hartigan, J., Smith, D. R., Suh, E., Papadopoulos, N., Buckhaults, P., Markowitz,S.D., Parmigiani, G., Kinzler, K.W., Velculescu, V.E. and Vogelstein, B. The genomic landscapes of human breast and colorectal cancers. Science 318: 1108-1113, 2007.
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