Laureates of the Japan Prize

-
アン・マクラーレン博士
【業績解説文】
2002 Japan Prize受賞者
主な受賞等
1967 |
Scientific Medal, Zoological Society, London |
1975 |
Fellow of the Royal Society |
1986 |
Fellow of the Royal College of Obstetricians and Gynaecologists |
1988 |
Foreign Member of Polish Academy of Sciences |
1990 |
Royal Medal, The Royal Society |
1993 |
Dame Commander of the Order of the British Empire (DBE) |
1995 |
Corresponding Member of Slovenian Academy of Sciences and Arts |
1998 |
Founder Fellow, Academy of Medical Sciences |
1999 |
Foreign Member of the Russian Academy of Sciences |
所属期間、学会等
|
The Royal Society |
|
Royal Institution 3. British Society for Developmental Biology |
|
Genetical Society |
|
Society for the Study of Fertility |
|
Zoological Society of London |
|
British Society for Population Studies |
|
National Mouse Club |
|
European Molecular Biology Organisation |
|
European Society for Human Reproduction and Embryology |
|
International Society of Differentiation |
学歴
1949年 |
オックスフォード大学修士 |
1952年 |
同 Ph.D. |
職歴
1952-55年 |
ロンドン大学研究員 |
1955-59年 |
王立ロンドン獣医科大学研究員 |
1959-74年 |
エジンバラ大学動物遺伝学研究部門研究員 |
1974-92年 |
医科学研究院哺乳類発生部門部長 |
1992-現在 |
ウエルカムがん研究所客員主任研究員 |
現職
主な著書と論文
- McLaren, A. and Biggers, J.D. (1958) Successful development and birth of mice cultivated in vitro as early embryos. Nature 182, 877-878.
- McLaren, A. and Michie, D. (1958) Factors affecting vertebral variation in mice.4. Experimental proof of the uterine basis of a maternal effect.JEEM 6, 645-659.
- McLaren, A. and Michie, D. (1959) Superpregnancy in the mouse. Implantation and foetal immortality after induced superovulation in females of various ages. J exp Biol 36, 281-300.
- Healy, M. J.R., McLaren, A. and Michie, D. (1960) Foetal growth in the mouse. Proc Roy Soc B 153, 367-379. Wellcome Trust/Cancer Research Campaign (CRC) Institute.
- McLaren, A. (1964) Immunological control of fertility in female mice. Nature 201, 582-585.
- McLaren, A. (1965) Genetic and environmental effects on foetal and placental growth in mice. J Reprod Fert 2, 79-98.
- McLaren, A. (1969) Stimulus and response during early pregnancy in the mouse. Nature 221, 739-741.
- McLaren, A. and Bowman, P. (1969) Mouse chimaeras derived from fusion of embryos differing by nine genetic factors. Nature 224, 238-240.
- McLaren, A. (1972) Numerology of development. Nature 239, 274-276.
- McLaren, A. (1975) Sex chimaerism and germ cell distribution in a series of chimaeric mice. J Embryol exp Morph 33, 205-216.
- De Felici, M. and Mclaren, A. (1982) Isolation of mouse primordial gem cells. Exp Cell Res 142, 477-482.
- McLaren, A., Simpson, E., Tomonari, K., Chandler, P. and Hogg, H. (1984) Male sexual differentiation in mice lacking H-Y antigen. Nature 312, 552-555.
- McLaren, A. (1988) The developmental history of female germ cells in mammals. In: Oxford Reviews of Reproductive Biology Chapter 4 Vol. 10, 162-179.
- McLaren, A., Simpson, E.,Epplen, J. T., Studer, R., Koopman, P., Evans, E. P., and Burgoyne, P. S., (1988) Location of the genes controlling H-Y antigen expression and testis determination on the mouse Y chromosome. Proc Natl Acad Sci 85, 6442-6445.
- McLaren, A. and Buehr, M. (1990) Development of mouse germ cells in cultures of fetal gonads. Cell Differentiation and Development 31, 185-195.
- Ginsburg, M., Snow, M. H. L. and McLaren, A. (1990) Primordial germ cells in the mouse embryo gastrulation. Development 110, 521-528.
- McLaren, A. (1995) Primordial germ cells in mammals In: Organization of the early vertebrate embryo (eds N Zagris, A M Duprat, A J Duston), Plenum Press, New York, pp.1-9.
- McLaren, A. and Southee, D. (1997) Entry of mouse germ cells into meiosis. Dev Biol 187, 107-113.
- Durcova-Hills, G., Ainscough, J.E. and McLaren, A. (2001) Pluripotential stem cells derived from migrating primordial cells. Differentiation 68, 220-226.